Spring Valley is an affluent neighborhood in northwest Washington, D.C., known for its large homes and tree-lined streets.

The neighborhood houses the main campus of American University at 4400 Massachusetts Avenue, as well as Wesley Theological Seminary at 4500 Massachusetts Avenue. Nebraska Avenue and Loughboro Road are to its south, Dalecarlia Parkway is to its west, and Massachusetts Avenue is to its northeast. Paradoxically, the neighborhood to the northeast is called American University Park, even though the bulk of the main campus is located in Spring Valley.